Director, Compliance

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking a strategic and enterprise-minded compliance leader to serve as Director, Compliance. Reporting to the Vice President of Compliance, this role will lead the development and implementation of compliance and privacy policies to align with the company’s commercial readiness, global expansion, and patient-first values.

This individual will serve as a key advisor to leaders across Commercial, Medical Affairs, Regulatory Affairs, R&D, and Information Sciences, shaping cross-functional compliance strategies, ensuring regulatory readiness, and embedding ethical frameworks into company operations. This role will also lead the enterprise privacy program and data protection initiatives, ensuring alignment with global regulatory standards and supporting the launch of innovative oncology therapies.

The Director will be responsible for leading compliance operations, interfacing external legal and regulatory entities, and building sustainable processes to uphold integrity, transparency, and patient trust at scale.

Essential Job Functions and Responsibilities

• Compliance Program Oversight

  • Serve as a strategic advisor to RevMed leadership on emerging compliance risks, global regulations, and mitigation strategies impacting long-range business planning.

  • Collaborate with department leaders to understand risk considerations, implement compliance-related policies, procedures, and support ongoing compliance initiatives.

  • Establish strong relationships with key internal stakeholders to understand future compliance needs.

  • Update risks assessment and develop risk mitigation strategies and methods to operationalize compliance.

  • Interface with Contracts function to design and manage a system to integrate compliance review with contract review and to address substantive compliance questions that arise in contracts.

  • Ensure company compliance with policies, state and federal laws and regulations.

  • Help select and direct the work of outside counsel and other consultants, define project objectives, and manage projects.

  • Maintain a current working knowledge of various laws, regulations, and industry guidance that affect the corporate-wide compliance program, including anti-kickback and fraud and abuse laws, transparency laws, Sunshine Act, OIG and DOJ guidelines, HIPAA, FDA, CMS, ACA, and industry standards, such as the PhRMA Code on Interactions with Healthcare Providers.

  • Influence and participate in cross-functional governance forums (e.g., launch committees, audit steering groups).

• Operational Governance

  • Oversee compliance operations, including policy development, SOP governance, training strategy, communication programs, and investigation protocols.

  • Establish and lead compliance metrics dashboards, reporting to senior leadership and the Audit Committee as needed.

  • Direct compliance due diligence, monitoring, and risk review related to third-party vendor engagement, promotional activity, and clinical partnerships.

  • Participate in CMS, state or health plan audits and reviews.

  • Gather and audit data, prepare, and validate the federal and state transparency reports such as the Sunshine Act.

  • Train employees in company standard operating procedures and compliance, and update and create additional training content.

  • Manage compliance investigations.

  • Develop and manage an effective compliance communication program for the organization, including promoting use of the compliance hotline, heightened awareness of the Code of Conduct and applicable compliance policies, procedures, ethics, and understanding of new and existing compliance issues and related policies and procedures.

• Privacy & Data Protection Program Management

  • Lead enterprise-wide privacy program, including global privacy notices, cross-border data transfer strategies, consent frameworks, and business unit-specific protocols.

  • Serve as the company’s primary point-of-contact for privacy risk assessments, data sharing evaluations, and incident response planning.

  • Partner with IT Security, Legal, Commercial Operations, and Data Governance functions to ensure secure and compliant use of customer and HCP data.

• External Engagement & Regulatory Preparedness

  • Oversee the preparation and submission of federal and state transparency reporting, including Open Payments (Sunshine Act) and ex-U.S. disclosure requirements.

  • Collaborate with external counsel on enforcement trends, legislative changes, and industry standards, proactively integrating updates into company processes.

• Leadership & Culture Development

  • Manage a team of compliance professionals, consultants, and cross-functional contributors to drive operational execution and cultural alignment.

  • Foster a proactive culture of compliance, ethics, and transparency through values-based leadership, communication, and coaching.

  • Partner with Talent and HR teams to ensure compliance elements are embedded into training, onboarding, and performance culture.

Required Skills, Experience and Education:

• JD from an ABA-accredited law school and current bar membership in good standing.

• Minimum of 10+ years of progressive experience in legal, compliance, or privacy leadership within the life sciences industry.

• Demonstrated experience leading compliance programs in support of U.S. product launches, preferably in oncology or specialty therapeutics.

• Deep knowledge of FDA, OIG, CMS, HIPAA, Sunshine Act, PhRMA Code, GDPR, and other global healthcare compliance and data privacy frameworks.

• Experience interfacing with U.S. and ex-U.S. regulatory agencies, including during audits, inspections, and market authorization stages.

• Strong leadership, team management, and cross-functional influencing skills in a matrixed and fast-paced environment.

• Excellent business judgment, communication, and strategic thinking skills.

Preferred Qualifications:

• Experience supporting international compliance frameworks and privacy regulations, including EMA, GDPR, Japan APPI, and EU cross-border rules.

• Previous involvement in building compliance infrastructure from the ground up during a company’s commercialization or IPO phase.

• Familiarity with modern compliance technologies, data governance tools, and privacy operations platforms.

• Background in life sciences, biotech, or oncology-focused commercial organizations.

The base salary range for this full-time position is $258,000 to $296,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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